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Indian J Exp Biol ; 2000 Aug; 38(8): 733-45
Article in English | IMSEAR | ID: sea-58851

ABSTRACT

Transgenics and gene targeting by homologous recombination provide an ideal opportunity to delineate immune functions of specific genes. These gene knockout mice are powerful tools to understand complex mechanism of immune system and molecular processes underlying autoimmune diseases and immunodeficiencies. Availability of an increased pool of genetically manipulated mice will provide a basic foundation for developing of novel strategies to treat immunological diseases.


Subject(s)
Animals , Gene Targeting , Genetic Vectors , Humans , Immune System , Mice , Mice, Knockout , Mice, Transgenic , Recombination, Genetic
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